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It's D. Olanzapine plus fluoxetine combination.

Explanation: Olanzapine plus fluoxetine combination and quetiapine are the two medications approved by the FDA for bipolar depression. Olanzapine plus fluoxetine combination carries a black-box warning for both components—selective serotonin reuptake inhibitors (SSRIs), which could increase the risk of suicide in individuals younger than 25 years; and antipsychotics, which may increase the risk of cerebrovascular accidents, including stroke, in elderly patients with dementia-related psychosis.

Muskin PR and Dickerman AL, eds. Study Guide to Psychiatry: A Companion to the American Psychiatric Publishing Textbook of Psychiatry, Sixth Edition. Arlington, VA: American Psychiatric Association Publishing; 2015: 38, 233. Click here to purchase. Members can purchase at a discount.