American Psychiatric Association

December 15, 2017 | View Online | Psychiatric News

TEST YOUR KNOWLEDGE

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What normal, age-related change in neurotransmitter input to the forebrain increases the likelihood of delirium from anticholinergic drugs?
A. Loss of pigmented cells in the substantia nigra, increasing the sensitivity of dopamine D2 receptors.
B. Loss of neurons in the nucleus basalis of Meynert and septal nuclei, increasing the cholinergic input to the forebrain.
C. Loss of pigmented cells in the substantia nigra, reducing the sensitivity of D2 receptors.
D. Loss of neurons in the nucleus basalis of Meynert and septal nuclei, reducing the cholinergic input to the forebrain.
E. Increase in pigmented cells in the substantia nigra, increasing the sensitivity of D2 receptors.

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